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Copper Peptides and Skin Care

by Sara Kitch

In snail organism tissues, glycosaminoglycans (GAGs) are primarily located inside granules and in the shell, and are secreted on the exterior of the shell as a mucous-like liquid. Snail glycosaminoglycan tightly unites divalent copper cations (Cu 2 ) that create copper peptides. This substance reportedly has skin regeneration properties. The proportion of copper in the snail mucins is notable.

Copper peptides have been shown to be effective in just minute quantities:

Copper-induced vascular endothelial growth factor expression and wound healing. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002 May;282(5):H1821-7.

Laboratory of Molecular Medicine, Department of Surgery, 512 Davis Heart & Lung Research Institute, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.

Angiogenesis, the formation of new blood vessels, plays a central role in injury curing. Among many known growth factors, the vascular endothelial growth factor (VEGF) is believed to be the most prevailing, efficacious, and long-term signal that is recognized to promote angiogenesis in injuries. Whereas the direct participation of copper in promoting angiogenesis has been known for the past two decades, the precise targets of copper action remained unclear.

This paper presents initial evidence, showing that inducible VEGF synthesis is sensitive to copper production, and that the angiogenic potential of copper may be harnessed to accelerate skin injury contraction and closure.

In relatively normal proportions, copper sulfate induced VEGF expression has be proven to mutate human keratinocytes. Copper shared some of the pathways utilized by hypoxia to regulate VEGF synthesis. Topical copper sulfate accelerated the closure of excisional murine skin injuries, allowing incisions to cure themselves by secondary intention. Copper-sensitive mechanisms regulate key intermediaries of injury healing, such as angiogenesis and extracellular matrix remodeling.

Copper-based treatment represents a feasible approach to promote skin injury healing, including it among the likely components of natural skin care treatments.

Certain kinds of copper peptide complexes possess both tissue protection and repairing abilities. Copper has defensive and rejuvenative actions on several organ systems includinggastric mucosa,bone, skin, hair follicles and intestinal linings. These kinds of copper complexes are increasingly included in cosmetic skin and hair care products because of their ability to trigger the regeneration of skin. You will find them among other dermatological skin renewal options, such as chemical peels, laser resurfacing and dermabrasion, to improve post-treatment skin recovery.

Stop Aging in its Tracks

The main interest in copper peptides is in the area of reversing the effects of human aging and UV harm of the human skin. During the aging process, skin becomes thinner and tends to accumulate several skin lesions and imperfections. Within the dermis and epidermis, thin and subcutaneous fat cells diminish in quantity.

Several studies have found that the application of copper peptide creams to the human skin is even more effective in promoting collagen production than retinoic acid or vitamin C. It also increases the thickness of the epidermis and dermis, improves cellular regeneration, reduces wrinkles and eliminates skin imperfections such as blotchiness and sun damage spots.

A natural skin treatment ingredient provides solutions fast, all-naturally. Natural ingredients ensure a safe and promising skin rejuvenation process.

Published March 7th, 2008

Filed in Beauty, Health